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Journal Article

Citation

Grunebaum MF, Galfalvy HC, Mortenson LY, Burke AK, Oquendo MA, Mann JJ. J. Affect. Disord. 2010; 123(1-3): 123-130.

Affiliation

Department of Psychiatry, Columbia University, and New York State Psychiatric Institute, United States.

Copyright

(Copyright © 2010, Elsevier Publishing)

DOI

10.1016/j.jad.2009.09.010

PMID

19819021

PMCID

PMC2860050

Abstract

OBJECTIVE: To study two aspects of interpersonal function - attachment security and social adjustment - in relation to suicide attempt and major depressive episode (MDE) during naturalistic follow-up of up to one year after presentation with MDE. METHOD: 136 adults who presented with a DSM-IV MDE completed the Adult Attachment Scale and the Social Adjustment Scale-Self Report at study entry. Based on follow-up interviews at three months and one year, we used survival analysis to investigate the relationship of scores on these measures with time to a suicide attempt and time to recurrent MDE. RESULTS: Less secure/more avoidant attachment predicted increased risk of suicide attempt during the 1-year follow-up (Wald chi(2)=9.14, df=1, p=0.003, HR=1.16, 95% CI=1.05 to 1.27). Poorer social adjustment predicted increased risk of recurrent MDE (Wald chi(2)=6.95, df=1, p=0.008, HR=2.36, 95% CI=1.25 to 4.46), and that in turn increased the risk of a suicide attempt (z=4.19, df=1, p<0.001, HR=17.3, 95% CI=4.6 to 65.5). CONCLUSIONS: Avoidant attachment in the setting of major depressive disorder is a potential therapeutic target to prevent suicidal behavior. Enhancing social adjustment may reduce relapse in major depressive disorder and thereby reduce risk of a suicide attempt. Study limitations include small sample size and use of a self-report attachment scale.


Language: en

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