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Journal Article

Citation

Schneider B, Wetterling T, Sargk D, Schneider F, Schnabel A, Maurer K, Fritze J. Eur. Arch. Psychiatry Clin. Neurosci. 2005; 256(1): 17-27.

Affiliation

Center of Psychiatry Department of Psychiatry and Psychotherapy, Johann Wolfgang Goethe-University Frankfurt/Main, Heinrich-Hoffmann-Str. 10, 60528, Frankfurt/Main, Germany.

Copyright

(Copyright © 2005, Holtzbrinck Springer Nature Publishing Group)

DOI

10.1007/s00406-005-0593-7

PMID

16133739

Abstract

There is a lack of psychological autopsy studies assessing the influence of axis I disorders on axis II disorders as risk factors for suicide. Therefore, we investigated the association between personality disorders, axis I disorders, and suicide. Psychiatric disorders were evaluated by a semi-structured interview including the Structured Clinical Interview for DSM-IV Axis I (SCID-I) and Personality Disorders (SCID-II) in 163 completed suicides (mean age 49.6 +/- 19.3 years; 64.4% men) and by personal interview in 396 populationbased control persons (mean age 51.6 +/- 17.0 years; 55.8% men). In both genders, suicides significantly more often had personality disorders of all clusters than controls, also after adjustment for axis I disorders (p < 0.001, each). In addition, alcohol-related disorders, major depression, and co-occurrence of personality disorders of more than one cluster (men: OR = 16.13; women: OR = 20.43) remained independent predictors for suicide in both genders,"pure" cluster B personality disorders only in women and "pure" cluster C personality disorders only in men. In both genders, co-occurrence of personality disorders of more than one cluster contributed to risk of completed suicide after control for axis I psychiatric disorders and has to be considered as an independent risk factor for suicide.

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