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Journal Article

Citation

Bonnett LJ, Tudur-Smith C, Williamson PR, Marson AG. Br. Med. J. BMJ 2010; 341: c6477.

Affiliation

Department of Biostatistics, University of Liverpool.

Copyright

(Copyright © 2010, BMJ Publishing Group)

DOI

unavailable

PMID

21147743

PMCID

PMC2998675

Abstract

After a single unprovoked seizure this reanalysis of MESS provides estimates of seizure recurrence risks that will inform policy and guidance about regaining an ordinary driving license. Further guidance is needed as to how such data should be utilized; in particular, whether a population approach should be taken with a focus on the unadjusted results or whether attempts should be made to individualize risk. Guidance is also required as to whether the focus should be on risk estimates only or on the confidence interval as well. If the focus is on the estimate only our unadjusted estimates suggest that treated and untreated patients are eligible to drive after being seizure-free for six months. If the focus is also on confidence intervals, direction is needed as to whether a conservative or liberal approach should be taken. Trial registration Current Controlled Trials ISRCTN98767960.


Language: en

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