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Journal Article

Citation

Schroeder SR, Ewing JA, Allen JA. J. Saf. Res. 1974; 6(2): 89-93.

Affiliation

University of North Carolina, Child Development Research Inst., Chapel Hill, NC, USA

Copyright

(Copyright © 1974, U.S. National Safety Council, Publisher Elsevier Publishing)

DOI

unavailable

PMID

unavailable

Abstract

Thirty healthy male students tracked a training film in a driving simulator after administration of combinations of alcohol and chlordiazepoxide or methapyrilene or combinations of any of the three drugs with a placebo. Although none of the combinations produced significant increases in driving errors, driver eye movements were affected. Alcohol suppressed eye movement frequency and restricted the useful field of view. Chlordiazepoxide had a moderate antagonistic effect, and methapyrilene had a strong antagonistic effect on the suppression of the saccadic frequency by alcohol. Eye movement parameters are seen as a sensitive measure of the synergistic effects of alcohol in combination with other drugs.

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