SAFETYLIT WEEKLY UPDATE

We compile citations and summaries of about 400 new articles every week.
RSS Feed

HELP: Tutorials | FAQ
CONTACT US: Contact info

Search Results

Journal Article

Citation

Leibson CL, Brown AW, Hall Long K, Ransom JE, Mandrekar JN, Osler TM, Malec JF. J. Neurotrauma 2012; 29(11): 2038-2049.

Affiliation

Mayo Clinic, Health Sciences Research, 200 First St SW, Rochester, Minnesota, United States, 55905; leibson.cynthia@mayo.edu.

Copyright

(Copyright © 2012, Mary Ann Liebert Publishers)

DOI

10.1089/neu.2010.1713

PMID

22414023

Abstract

Data on TBI economic outcomes are limited. We used Rochester Epidemiology Project (REP) resources to estimate long-term medical costs for clinically-confirmed incident TBI across the full range of severity and controlling for pre-existing conditions and co-occurring injuries. All Olmsted County, MN, residents with diagnoses indicative of potential TBI 1985-2000 (N=46,114) were identified; a random sample (N=7,175) was selected for medical-record review to confirm case status and characterize as definite (moderate/severe), probable (mild), or possible (symptomatic) TBI. For each case, we identified one age- sex-matched non-TBI control registered in REP in the year (±1) of case's TBI. Cases with co-occurring non-head injuries were assessed for non-head-injury severity and assigned similar non-head-injury-severity controls. The 1,145 case/control pairs for 1988-2000 were followed until earliest death/emigration of either member for medical costs 12-months before and up to 6 years after baseline, i.e., injury date for cases and comparable dates for controls. Differences between case and control costs were stratified by TBI severity, as defined by evidence of brain injury; comparisons used Wilcoxon signed-rank plus multivariate modeling (adjusted for pre-baseline characteristics). From baseline-6 years, each TBI category exhibited significant incremental costs. For definite and probable TBI, most incremental costs occurred within the first 6 months; significant long-term incremental medical costs were not apparent among 1-year survivors. By contrast, cost differences between possible TBI cases and controls were not as great within the first 6 months but were substantial among 1 year survivors. Although mean incremental costs were highest for definite cases, probable and possible cases accounted for >90% of all TBI events and 66% of total incremental costs. Preventing probable and possible events might contribute substantial reductions in TBI-associated medical care costs.


Language: en

NEW SEARCH


All SafetyLit records are available for automatic download to Zotero & Mendeley
Print