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Citation |
Nakata H, Sakamoto K, Otsuka A, Yumoto M, Kakigi R. Clin. Neurophysiol. 2013; 124(2): 273-282. |
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Affiliation |
Department of Integrative Physiology, National Institute for Physiological Sciences, Okazaki, Japan; Department of Clinical Laboratory, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan; Faculty of Sport Sciences, Waseda University, Tokorozawa, Japan. |
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Copyright |
(Copyright © 2013, Elsevier Publishing) |
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DOI |
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PMID |
22863416 |
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Abstract |
OBJECTIVE: We investigated the characteristics of cortical rhythmic activity in No-go processing during somatosensory Go/No-go paradigms, by using magnetoencephalography (MEG). METHODS: Twelve normal subjects performed a warning stimulus (S1) - imperative stimulus (S2) task with Go/No-go paradigms. The recordings were conducted in three conditions. In Condition 1, the Go stimulus was delivered to the second digit, and the No-go stimulus to the fifth digit. The participants responded by pushing a button with their right thumb for the Go stimulus. In Condition 2, the Go and No-go stimuli were reversed. Condition 3 was the resting control. RESULTS: A rebound in amplitude was recorded in the No-go trials for theta, alpha, and beta activity, peaking at 600-900ms. A suppression of amplitude was recorded in Go and No-go trials for alpha activity, peaking at 300-600ms, and in Go and No-go trials for beta activity, peaking at 200-300ms. CONCLUSION: The cortical rhythmic activity clearly has several dissociated components relating to different motor functions, including response inhibition, execution, and decision-making. SIGNIFICANCE: The present study revealed the characteristics of cortical rhythmic activity in No-go processing. Language: en |