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Citation |
Filimon F, Philiastides MG, Nelson JD, Kloosterman NA, Heekeren HR. J. Neurosci. 2013; 33(5): 2121-2136. |
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Affiliation |
Max Planck Institute for Human Development, Berlin 14195, Germany, School of Psychology, University of Nottingham, Nottingham NG7 2RD, United Kingdom, Division of Psychology and Language Sciences, University College London, London WC1E 6BT, United Kingdom, Department of Psychology, University of Amsterdam, 1018XA, Amsterdam, The Netherlands, and Department of Education and Psychology, and Dahlem Institute for the Neuroimaging of Emotion, Freie Universität Berlin, Berlin D-14195. |
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Copyright |
(Copyright © 2013, Society for Neuroscience) |
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DOI |
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PMID |
23365248 |
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Abstract |
The extent to which different cognitive processes are "embodied" is widely debated. Previous studies have implicated sensorimotor regions such as lateral intraparietal (LIP) area in perceptual decision making. This has led to the view that perceptual decisions are embodied in the same sensorimotor networks that guide body movements. We use event-related fMRI and effective connectivity analysis to investigate whether the human sensorimotor system implements perceptual decisions. We show that when eye and hand motor preparation is disentangled from perceptual decisions, sensorimotor areas are not involved in accumulating sensory evidence toward a perceptual decision. Instead, inferior frontal cortex increases its effective connectivity with sensory regions representing the evidence, is modulated by the amount of evidence, and shows greater task-positive BOLD responses during the perceptual decision stage. Once eye movement planning can begin, however, an intraparietal sulcus (IPS) area, putative LIP, participates in motor decisions. Moreover, sensory evidence levels modulate decision and motor preparation stages differently in different IPS regions, suggesting functional heterogeneity of the IPS. This suggests that different systems implement perceptual versus motor decisions, using different neural signatures. Language: en |