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Journal Article

Citation

Kishore S, Hornick N, Sato N, Page WK, Duffy CJ. Cereb. Cortex 2012; 22(1): 201-208.

Affiliation

Department of Neurology, University of Rochester Medical Center, Rochester, NY 14642, USA.

Copyright

(Copyright © 2012, Oxford University Press)

DOI

10.1093/cercor/bhr115

PMID

21653287

PMCID

PMC3236797

Abstract

We presented naturalistic combinations of virtual self-movement stimuli while recording neuronal activity in monkey cerebral cortex. Monkeys used a joystick to drive to a straight ahead heading direction guided by either object motion or optic flow. The selected cue dominates neuronal responses, often mimicking responses evoked when that stimulus is presented alone. In some neurons, driving strategy creates selective response additivities. In others, it creates vulnerabilities to the disruptive effects of independently moving objects. Such cue interactions may be related to the disruptive effects of independently moving objects in Alzheimer's disease patients with navigational deficits.


Language: en

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