Citation

Sørup FH, Neumann AB, Holst H. Ugeskr. Laeger 2014; 176(23): ePub.

Affiliation

Klinisk Farmakologisk Afdeling, -Bispebjerg Hospital, Bispebjerg Bakke 23, 2400 København NV. fsoe0011@regionh.dk.

Copyright

(Copyright © 2014, Den Alm Danske Laegerforening)

DOI

unavailable

PMID

25352081

Abstract

Varenicline is a partial agonist on cerebral nicotine receptors and is indicated for smoking cessation. There are only a few case reports of intended overdose of varenicline. We report a history of a 45-year-old woman who ingested 40-50 mg varenicline. She spontaneously vomited shortly after ingestion which may be due to varenicline's effect on gastrointestinal 5-hydroxytryptamine3-receptors. At admission to hospital she received activated charcoal. ECG-monitoring and blood samples were all normal. She was discharged the following day.

Language: da