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Journal Article

Citation

Ferner RE. Br. J. Clin. Pharmacol. 2014; 77(3): 403-409.

Affiliation

West Midlands Centre for Adverse Drug Reactions, City Hospital, Birmingham, B18 7QH; School of Clinical and Experimental Medicine, University of Birmingham, B15 2TT, UK.

Copyright

(Copyright © 2014, John Wiley and Sons)

DOI

10.1111/bcp.12156

PMID

23683079

PMCID

PMC3952715

Abstract

Rational therapeutics requires a balance between benefits and harms. (i) Harm may be inevitable. Some adverse drug reactions cannot be predicted or prevented. (ii) Some harm occurs in error when a medicine is wrongly formulated, prescribed, dispensed or administered. Adverse drug reactions that might have been prevented, for example, by monitoring, fall into this category. (iii) Rarely, harm is inflicted deliberately, for example, in murder by poisoning. Here I consider adverse drug reactions, errors and deliberate drug-induced harm from the perspective of a clinical pharmacologist.


Language: en

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