Citation

Bellón JA, Moreno-Peral P, Motrico E, Rodríguez-Morejón A, Fernández A, Serrano-Blanco A, Zabaleta-Del-Olmo E, Conejo-Cerón S. Prev. Med. 2015; 76(Suppl 1): S22-S32.

Affiliation

Instituto de Investigación Biomédica de Málaga (IBIMA), Unidad de Investigación del Distrito de Atención Primaria Málaga-Guadalhorce, Málaga, Spain. Electronic address: soniafundacionimabis@hotmail.com.

Copyright

(Copyright © 2015, Elsevier Publishing)

DOI

10.1016/j.ypmed.2014.11.003

PMID

25445331

Abstract

OBJECTIVE: To determine the effectiveness of psychological and/or educational interventions to prevent the onset of episodes of depression.

METHODS: Systematic review of systematic reviews and meta-analyses (SR/MA). We searched PubMed, PsycINFO, Cochrane Database of Systematic Reviews, OpenGrey, and PROSPERO from their inception until February 2014. Two reviewers independently evaluated the eligibility criteria of all SR/MA, abstracted data, and determined bias risk (AMSTAR).

RESULTS: Twelve SR/MA (156 non-repeated trials and 56,158 participants) were included. Of these, 142 (91%) were randomized-controlled, 13 (8.3%) controlled trials, and 1 (0.6%) had no control group. Five SR/MA focused on children and adolescents, four on specific populations (women after childbirth, of low socioeconomic status, or unfavorable circumstances; patients with severe traumatic physical injuries or stroke) and three addressed the general population. Nine (75%) SR/MA concluded that interventions to prevent depression were effective. Of the 156 trials, 137 (87.8%) reported some kind of effect size calculation. Effect sizes were small in 45 (32.8%), medium in 26 (19.1%), and large in 25 (18.2%) trials; 41 (29.9%) trials were not effective. Of the 141 trials for which follow-up periods were available, only 34 (24.1%) exceeded 12months.

CONCLUSION: Psychological and/or educational interventions to prevent onset of episodes of depression were effective, although most had small or medium effect sizes.

Language: en