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Journal Article

Citation

Nasa P, Juneja D. Indian J. Crit. Care Med. 2016; 20(12): 739-741.

Affiliation

Department of Critical Care Medicine, Sri Balaji Action Medical Institute, New Delhi, India.

Copyright

(Copyright © 2016, Indian Society of Critical Care Medicine, Publisher Medknow Publications)

DOI

10.4103/0972-5229.195716

PMID

28149034

Abstract

Amitraz is used as a pesticide in agricultural and veterinary medicine. It is primarily a central α2 adrenergic agonist and known to cause central nervous system depression, convulsions, respiratory depression, and bradycardia on severe intoxication. We report a case of a 3-year-old child who presented with accidental ingestion of amitraz solution with signs of severe poisoning. There is no specific antidote of amitraz poisoning in humans, however, animal experiments with α2 adrenergic antagonists such as yohimbine and atimepazole have been successful. The child was managed besides intensive management with enteral yohimbine, and he regained consciousness in 18 h and was successfully weaned off mechanical ventilation.


Language: en

Keywords

Amitraz poisoning; poisoning; yohimbine

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