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Journal Article

Citation

Webster GD, Gabler HC. Annu. Proc. Assoc. Adv. Automot. Med. 2007; 51: 449-464.

Affiliation

Virginia Polytechnic and State University, Center for Injury Biomechanics, Blacksburg, VA.

Copyright

(Copyright © 2007, Association for the Advancement of Automotive Medicine)

DOI

unavailable

PMID

18184507

PMCID

PMC3217504

Abstract

Transdermal ethanol detection is a promising method that could prevent drunk driving if integrated into an ignition interlock system. However, experimental data from previous research has shown significant time delays between alcohol ingestion and detection at the skin which makes real time estimation of blood alcohol concentration via skin measurement difficult. Using a validated model we studied the effects that body weight, metabolic rate and ethanol dose had on the time lag between the blood alcohol concentration and transdermal alcohol concentration. The dose of alcohol ingested was found to have the most significant effect on the skin alcohol lag time; a dose of 15 ml of ethanol resulted in a peak lag time of approximately 33 minutes, while a dose of 60 ml of ethanol resulted in a peak time lag of 53 minutes. The time lag was found to be insensitive to body mass and only moderately sensitive to changes in metabolic rates.


Language: en

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