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Journal Article

Citation

Lia K, Spigset O, Slørdal L. Tidsskr. Nor. Laegeforen. 2009; 129(2): 105-108.

Vernacular Title

Kjoring under pavirkning av amfetamin og metamfetamin.

Affiliation

Institutt for laboratoriemedisin, barne- og kvinnesykdommer Norges teknisk-naturvitenskapelige universitet.

Copyright

(Copyright © 2009, Norske Laegeforening)

DOI

10.4045/tidsskr.09.34091

PMID

19151802

Abstract

BACKGROUND: The CNS stimulatory agents amphetamine and methamphetamine are often detected in blood samples from apprehended subjects driving under the influence of drugs. MATERIAL AND METHODS: Relevant literature was identified through searches in PubMed and Google Scholar. The current state of knowledge regarding effects of amphetamines on traffic behaviour is reviewed and discussed. RESULTS: Limited epidemiological data and a small number of experimental studies using low doses of amphetamines are available. Low amphetamine doses have been associated with enhanced performance in studies of sleep-deprived subjects. Theoretical considerations and empirical observations suggest that higher doses may impede performance, but not in accordance with usual concentration/effect relationships. INTERPRETATION: There is a conspicuous lack of data on how to handle cases of driving under the influence of amphetamines.


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