TY - JOUR PY - 2012// TI - Nonlinear indices of circadian changes in individuals with dementia and aggression JO - Psychiatry research A1 - Etcher, Luann A1 - Whall, Ann A1 - Kumar, Rahul A1 - Devanand, Davangere A1 - Yeragani, Vikram SP - 77 EP - 78 VL - 199 IS - 1 N2 - Nonlinear analyses of actigraphy data were utilized to investigate circadian rest-activity system motor control in nursing-home residents with dementia and with/without aggressive behavior (AB). Significant differences observed between groups in measures of approximate entropy (ApEn) and fractal dimension (FD). ApEn and FD are sensitive to detecting and characterizing discrete changes in central motoric control and temporality of behaviors in dementia. Findings may inform understanding of clinical heterogeneity and possible physiologic sub-classifications of Alzheimer's dementia.
Language: en
LA - en SN - 0165-1781 UR - http://dx.doi.org/10.1016/j.psychres.2012.03.042 ID - ref1 ER -