Citation

Romão W, Sabino BD, Bueno MI, Vaz BG, Júnior AC, Maldaner AO, de Castro EV, Lordeiro RA, Nascentes CC, Eberlin MN, Augusti R. J. Forensic Sci. 2012; 57(5): 1307-1312.

Affiliation

ThoMSon Mass Spectrometry Laboratory, Institute of Chemistry, State University of Campinas - UNICAMP, Campinas, SP, 13084-971, Brazil; Department of Chemistry, Federal University of Espírito Santo, Vitória, ES, 29075-910, Brazil.

Copyright

(Copyright © 2012, American Society for Testing and Materials, Publisher John Wiley and Sons)

DOI

10.1111/j.1556-4029.2012.02237.x

PMID

22880936

Abstract

Normally, the identification of the LSD drug is performed by forensic laboratories, using the Ehrlich spot test. However, this is a nonspecific analysis. Additionally, the Brazilian Federal Police has identified the presence of a new compound in seized blotters: 9,10-dihydro-LSD, an uncontrolled substance. In this work, easy ambient sonic-spray ionization mass spectrometry in the positive ion mode, EASI(+)-MS, was used to characterize LSD and 9,10-dihydro-LSD compositions directly from the surface of blotters. The presence of LSD in the seized blotter samples were also confirmed via high-performance liquid chromatography with ultraviolet detector. In a set of 41 blotters analyzed by EASI(+)-MS, 28 showed positive results for LSD, seven for 9,10-dihydro-LSD, and another six samples showed negative results for both LSD and 9,10-dihydro-LSD. The combination of thin layer chromatography with EASI-MS also demonstrated to be a relatively simple and powerful screening tool for forensic analysis of street drugs.

Language: en