Citation

Havier RG, Lin R. J. Forensic Sci. 1985; 30(2): 563-566.

Copyright

(Copyright © 1985, American Society for Testing and Materials, Publisher John Wiley and Sons)

DOI

unavailable

PMID

3998703

Abstract

Toxicological findings are described in 16 medical examiner cases directly related to the combination of codeine and glutethimide. The cases described represent a six-month period, July through December 1982, showing the epidemic rate of abuse of this drug combination, most prominent in the Newark, NJ area since the late 1970s. Concentrations of codeine and glutethimide, measured by gas liquid chromatography (GLC), in the blood averaged 0.62 and 4.07 mg/L, respectively. Similarly determined urine concentrations averaged 38.06 and 12.68 mg/L, respectively. Specific concentrations of each drug in most cases were in the high therapeutic range, suggesting a possible toxic synergistic effect.

Language: en