Citation

Sekine H, Nakahara Y. J. Forensic Sci. 1987; 32(5): 1271-1280.

Affiliation

Criminal Investigation Laboratory, Saitama Prefecture Police Headquarters, Japan.

Copyright

(Copyright © 1987, American Society for Testing and Materials, Publisher John Wiley and Sons)

DOI

unavailable

PMID

3668479

Abstract

Experiments of smoking methamphetamine in tobacco have been investigated. Inhalation efficiencies of methamphetamine into tar were 6 to 17% according to the additive amounts, suction volume, and intervals of smoking. Major pyrolysis products of methamphetamine in tar were identified as methamphetamine, amphetamine, phenylacetone, dimethylamphetamine, N-formyl-, N-acetyl-, N-propionyl-, and N-cyanomethyl-methamphetamine by the spectral analysis of infrared spectra (IR), mass spectra (MS), and proton magnetic resonance spectra (PMR), and comparison with the samples synthesized from authentic samples by one step. The largest pyrolysis product was N-cyanomethylmethamphetamine which is a new compound and easily metabolized to methamphetamine in the body. Methamphetamine itself transferred into tar was not so large, but the total active compounds in tar which would be metabolized to methamphetamine in the body were considerably larger.

Language: en