Citation

Fiori LM, Wanner B, Jomphe V, Croteau J, Vitaro F, Tremblay RE, Bureau A, Turecki G. PLoS One 2010; 5(11): e15146.

Affiliation

McGill Group for Suicide Studies, Douglas Mental Health University Institute, McGill University, Montreal, Quebec, Canada.

Copyright

(Copyright © 2010, Public Library of Science)

DOI

10.1371/journal.pone.0015146

PMID

21152090

PMCID

PMC2994870

Abstract

These results demonstrate that genetic variants in polyaminergic genes are associated with psychiatric conditions, each of which involves a set of separate and distinct risk alleles. As several of these polymorphisms are associated with gene expression, these findings may provide mechanisms to explain the alterations in polyamine metabolism which have been observed in psychiatric disorders.

Language: en