Citation

Ul Abideen Z, Mahmud SN, Rasheed A, Farooq Qasim Y, Ali F. Cureus 2017; 9(6): e1305.

Affiliation

Nephrology, Shifa International Hospital, Islamabad, Pakistan.

Copyright

(Copyright © 2017, Curēus)

DOI

10.7759/cureus.1305

PMID

28690939

PMCID

PMC5493463

Abstract

Carbon monoxide poisoning is common and carries significant morbidity and mortality. The nervous system, particularly the brain, is frequently affected by it, owing to its high metabolic activity and oxygen requirements. Carbon monoxide damages the nervous system by both hypoxic and inflammatory mechanisms. Central diabetes insipidus is an extremely rare complication of carbon monoxide poisoning. Herein, we report the case of a young lady, who developed this complication and severe hypernatremia after accidental carbon monoxide poisoning. She also developed a hyperglycemic hyperosmolar state during the treatment for hypernatremia. To the best of our knowledge, both these entities have not been reported together in association with carbon monoxide poisoning. The purpose of this article is to emphasize the anticipation and early recognition of central diabetes insipidus in carbon monoxide poisoning. This can prevent severe hypernatremia and complications associated with its presence and treatment.

Language: en

Keywords

carbon monoxide; central diabetes insipidus; hypernatremia; hyperosmolar hyperglycemic state; polyuria