Citation

Grinberg LT, Anghinah R, Nascimento CF, Amaro E, Leite RP, Martin Mda G, Naslavsky MS, Takada LT, Filho WJ, Pasqualucci CA, Nitrini R. J. Alzheimers Dis. 2016; 54(1): 169-174.

Affiliation

Department of Neurology, University of São Paulo Medical School, São Paulo, Brazil.

Copyright

(Copyright © 2016, IOS Press)

DOI

10.3233/JAD-160312

PMID

27472879

PMCID

PMC5293758

Abstract

The relationship between soccer and chronic traumatic encephalopathy (CTE) is not well established. We report clinicopathological correlations in an 83-year-old retired center-back soccer player, with no history of concussion, manifesting typical Alzheimer-type dementia. Examination revealed mixed pathology including widespread CTE, moderate Alzheimer's disease, hippocampal sclerosis, and TDP-43 proteinopathy. This case adds to a few CTE cases described in soccer players. Furthermore, it corroborates that CTE may present clinically as typical Alzheimer-type dementia. Further studies investigating the extent to which soccer is a risk for CTE are needed.

Language: en

Keywords

Alzheimer’s disease; autopsy; chronic post-traumatic encephalopathy; dementia; humans; soccer