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Journal Article

Citation

Panda PK, Raj A, Singh SS. Curr. Drug Saf. 2018; 13(2): 144-147.

Affiliation

Andaman Nicobar Islands Institute of Medical Science (ANIIMS). India.

Copyright

(Copyright © 2018, Bentham Science Publishers)

DOI

10.2174/1574886313666180313120659

PMID

29532759

Abstract

Treatments of patient with amlodipine (a calcium channel blocker, CCB) overdose/poisoning remain challenging and death is certain if not intervened timely. Furthermore, for a society, the availability and common use of this drug make more vulnerable, especially by children, towards an accidental/suicidal poisoning. Here we describe an adolescent school girl who took 150 mg of amlodipine and was admitted in our hospital approximately 4 hours after ingestion with suicidal intention. She developed circulatory failure and tachypnea. Decontamination, calcium, glucagon, and dual vasopressors were started, however, persistent hypotension led to initiation of hyperinsulinemic euglycemia therapy. She recovered fully and discharged in few days without any complications. This case educates not only about the successful use of variant drugs in the management of CCB overdose/poisoning, but also alarms the society for a safety storage of often used drugs, especially away from children/adolescents.

Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.org.


Language: en

Keywords

Calcium channel blocker; Hyperinsulemic euglycemic therapy; Overdose; Suicide intention

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