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Journal Article

Citation

Issan Y, Avlas O, Daniel O. J. Forensic Sci. 2019; 64(3): 852-856.

Affiliation

DNA Database Laboratory, Division of Identification and Forensic Science (DIFS), Israel Police, Jerusalem, Israel.

Copyright

(Copyright © 2019, American Society for Testing and Materials, Publisher John Wiley and Sons)

DOI

10.1111/1556-4029.13915

PMID

30231298

Abstract

DNA analysis is a key method for the identification of human remains in mass disasters. Reference samples from relatives may be used to identify missing persons by kinship analysis. Different methods of applying the CODIS in disaster victim identification (DVI) were investigated. Two searches were evaluated: (i) relating family relatives to a pedigree tree (FPT) and (ii) relating unidentified human remains to a pedigree tree (UPT). A joint pedigree likelihood ratio (JPLR) and rank were calculated for each search. Both searches were similar in average JPLR and rank. In exceptional cases, namely the existence of a mutation different from the CODIS model, a nonbiological father, a mistake in STR, or incorrect profile association, the UPT search returned one true rank, whereas the FPT search returned no results. This paper suggests a novel strategy to overcome these limitations and increase efficiency in conducting identification of mass disaster victims.

© 2018 American Academy of Forensic Sciences.


Language: en

Keywords

amelogenin; combined DNA index system; disaster victim identification; forensic science; joint pedigree likelihood ratio; mass disaster; short tandem repeat

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