Citation

Tong F, Yang Y, Liang Y, Lopsong TZ, Liu YL, Zhao SQ, He GL, Zhou YW. Fa Yi Xue Za Zhi 2020; 36(1): 99-103.

Affiliation

Department of Forensic Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China.

Copyright

(Copyright © 2020, Si fa bu Si fa jian ding ke xue ji shu yan jiu suo)

DOI

10.12116/j.issn.1004-5619.2020.01.019

PMID

32250087

Abstract

The number of death from insulin overdose, including accidental poisoning, suicide and homicide, is increasing these years. The forensic diagnosis of death from insulin overdose is a tough task. Glucose is the main energy source of the brain. Therefore, hypoglycemic brain damage is considered to be the main reason of death from insulin overdose. Recently, research of hypoglycemic brain damage caused by insulin overdose is gradually being paid attention in the field of forensic medicine. This paper summarizes the neuropathologic changes, pathophysiologic process and potential neural molecular markers of hypoglycemic brain damage caused by insulin overdose in terms of forensic neuropathology, providing reference for the research and practice in forensic medicine related fields.

Copyright© by the Editorial Department of Journal of Forensic Medicine.

Language: zh

Language: zh

Language: zh

Language: zh

Keywords

forensic pathology; insulin; brain damage; hypoglycemia; review