
@article{ref1,
title="Suicide and suicidal ideation in Parkinson's disease",
journal="Journal of the neurological sciences",
year="2010",
author="Kostić, Vladimir S. and Pekmezović, Tatjana and Tomić, Aleksandra and Ječmenica-Lukić, Milica and Stojković, Tanja and Spica, Vladana and Svetel, Marina and Stefanova, Elka and Petrović, Igor and Džoljić, Eleonora",
volume="289",
number="1-2",
pages="40-43",
abstract="Little is known about the prevalence and correlates of suicidal behavior in Parkinson's disease (PD). In the first part of the study, we followed a cohort of 102 consecutive PD patients for 8years and found that the suicide-specific mortality was 5.3 (95% CI 2.1-12.7) times higher than expected. In the second part, we tested 128 PD patients for death and suicidal ideation and administered an extensive neurological, neuropsychological and psychiatric battery. Current death and/or suicidal ideation was registered in 22.7%. On univariate logistic regression analysis, psychiatric symptoms (depression, but also anxiety and hopelessness), but not the PD-related variables, were associated with such ideation. On multivariate logistic regression analysis this association held for major depression (odds ratio=4.6; 95% CI 2.2-9.4; p<0.001), psychosis (odds ratio=19.2; 95% CI 1.4-27.3; p=0.026), and increasing score of the Beck Hopelessness Scale (odds ratio=1.2; 95% CI 1.0-1.4; p=0.008). In conclusion, the suicide risk in PD may not be as high as it is expected, but it is certainly not trivial. According to our data almost a quarter of PD patients had death and/or suicidal ideation, that may significantly influence their quality of life.<p /><p>Language: en</p>",
language="en",
issn="0022-510X",
doi="10.1016/j.jns.2009.08.016",
url="http://dx.doi.org/10.1016/j.jns.2009.08.016"
}