@article{ref1,
title="Increased plasma nitric oxide metabolites in suicide attempters",
journal="Neuropsychobiology",
year="2006",
author="Lee, Bun-Hee and Lee, Sung-Woo and Yoon, DongKeun and Lee, Heng-Ju and Yang, Jiann C. and Shim, Se-Hoon and Kim, Da-Hye and Ryu, Seung-Ho and Han, Cholsung and Kim, Yong-Ku",
volume="53",
number="3",
pages="127-132",
abstract="OBJECTIVE: To evaluate any correlation between plasma levels of nitric oxide metabolites (NO(x)) and suicide attempt. METHOD: Plasma NO(x) levels were measured in 53 patients who had recently attempted suicide, 58 non-suicidal psychiatric patients, and 75 normal controls. The severity of suicidal behaviors was evaluated using Weisman and Worden's Risk-Rescue Rating Scale. RESULTS: Plasma NO(x) levels were significantly higher in suicidal patients than non-suicidal psychiatric patients or normal control subjects (F=11.029, d.f.=2, 183, p<0.001). Among the patients with a diagnosis of major depression, suicidal depressive patients had significantly higher plasma NO(x) levels than non-suicidal depressive patients (t=-3.090, d.f.=84, p=0.003). CONCLUSION: Our study suggests that increased NO production in plasma is associated with suicide attempt, especially in depressive patients.<p /> <p>Language: en</p>",
language="en",
issn="0302-282X",
doi="10.1159/000092542",
url="http://dx.doi.org/10.1159/000092542"
}