@article{ref1,
title="The serotonin transporter promoter polymorphism and suicide",
journal="Neuroscience letters",
year="2006",
author="Helbecque, Nicole and Sparks, D. L. and Hunsaker, John C. and Amouyel, Philippe",
volume="400",
number="1-2",
pages="13-15",
abstract="Serotonergic dysfunction has been implicated in mood disorders and in the pathophysiology of suicidality. A functional polymorphism (a 44-base pair insertion (L)/deletion (S)) in the promoter of the gene encoding the serotonin transporter (5-HTTLPR), associated with mood disorders, has been inconsistently associated with suicidality. To add to this debate, we designed a case-control study involving 62 suicide victims and 72 controls matched for age, gender and ethnicity. All subjects underwent forensic investigation. No association could be detected between the 5-HTTLPR polymorphism and suicide. This result is consistent with the proposal that different genes are involved in hopelessness and suicidal behavior or in depressive illness.<p /> <p>Language: en</p>",
language="en",
issn="0304-3940",
doi="10.1016/j.neulet.2006.02.012",
url="http://dx.doi.org/10.1016/j.neulet.2006.02.012"
}