@article{ref1,
title="Psychomotor performance and real driving performance of outpatients receiving diazepam",
journal="Psychopharmacology",
year="1981",
author="De Gier, Johan J. and 't Hart, Betsy J. and Nelemans, F. A. and Bergman, H.",
volume="73",
number="4",
pages="340-344",
abstract="The primary aim of this study was to compare task performance in a laboratory test and real driving performance of outpatients receiving diazepam medication with those of control subjects. Plasma and saliva samples were taken to investigate a level-response relationship. Real driving performance was measured by trained observers. The design of the laboratory test was based on a vigilance task (high attention) directly followed by a simple eye-hand coordination tasks (low attention). Twenty-two males participated in the study. Diazepam was given orally by prescription, mostly as a maintenance dose of 5 mg three times a day. Patients receiving diazepam showed impaired performance in the driving test and the low-attention task. Furthermore, the results indicate no relationship between plasma or saliva levels of diazepam and/or its metabolite N-desmethyldiazepam and real driving performance and/or laboratory task performance.<p /><p>Language: en</p>",
language="en",
issn="0033-3158",
doi="",
url="http://dx.doi.org/"
}