@article{ref1,
title="Diurnal rhythms of plasma cortisol, beta-endorphin and prolactin, and cerebrospinal fluid amine metabolite levels before suicide. Case report",
journal="Neuropsychobiology",
year="1986",
author="Dent, R. R. and Ghadirian, A. M. and Kusalic, M. and Young, Simon N.",
volume="16",
number="2-3",
pages="64-67",
abstract="There are indications to suggest a relationship between low levels of 5-hydroxy-indoleacetic acid (5HIAA) in the cerebrospinal fluid and suicidal behavior. Many depressed patients show an elevated cortisol secretion. As beta-endorphin is derived from the same precursor as ACTH, it is expected that plasma beta-endorphin levels will also rise in depressed patients. We report here a case of severe depression with diurnal variation who showed low CSF 5HIAA prior to his suicide. In contrast, his catecholamine metabolites were 50% above the mean values of other depressed patients. Hormonal measurements, however, showed low cortisol, prolactin and beta-endorphin levels.<p /><p>Language: en</p>",
language="en",
issn="0302-282X",
doi="",
url="http://dx.doi.org/"
}