@article{ref1,
title="Biological markers in depression",
journal="Psychopathology",
year="1986",
author="Bunney, W. E. Jr and Garland-Bunney, B. and Patel, S. B.",
volume="19",
number="Suppl 2",
pages="72-78",
abstract="This paper presents a brief review of markers and their potential uses in the study and treatment of affective illness. Some of these include the use of markers as aids in: diagnosis, selection of medication, prediction of relapse, and prediction of suicide. The use of combinations of markers to improve accuracy and the use of markers during the well-state will be discussed. A review of the literature suggests some promising candidates as markers of affective illness including the serotonin metabolite, 5 HIAA; 3H-imipramine platelet binding; REM induction using M-1 muscarinic agonists; and melatonin. Finally, a strategy using gene mapping techniques as a possible method of detecting additional markers is presented.<p /><p>Language: en</p>",
language="en",
issn="0254-4962",
doi="",
url="http://dx.doi.org/"
}