@article{ref1,
title="Peripheral serotonergic markers in patients with suicidal behavior",
journal="European Neuropsychopharmacology",
year="1991",
author="Simonsson, P. and Träskman-Bendz, Lil and Alling, C. and Oreland, Lars and Regnell, G. and Ohman, R.",
volume="1",
number="4",
pages="503-510",
abstract="Peripheral serotonergic parameters were studied in 17 patients with a history of suicidal behavior and in 17 age- and sex-matched healthy controls. Serotonin2 receptor function in platelets, measured as serotonin-induced 32P.phosphatidylinositol 4,5-bisphosphate hydrolysis, was significantly higher in patients than in age- and sex-matched controls. Increased serotonin2 receptor transduction was not correlated to psychiatric diagnosis, drug treatment or a history of violent suicide attempt. Monoamine oxidase activity was lower in platelets from patients with a history of suicidal behavior than in controls. In addition, whole blood serotonin was analyzed but no significant alterations were found in blood from patients.<p /> <p>Language: en</p>",
language="en",
issn="0924-977X",
doi="",
url="http://dx.doi.org/"
}