
@article{ref1,
title="Brain beta-adrenoceptor binding sites in depressed suicide victims: effects of antidepressant treatment",
journal="Psychopharmacology",
year="1991",
author="De Paermentier, F. and Cheetham, S. C. and Crompton, M. R. and Katona, C. L. and Horton, R. W.",
volume="105",
number="2",
pages="283-288",
abstract="beta-Adrenoceptor binding sites were measured by saturation binding of 3H.CGP 12177 in nine brain regions from 13 suicides, with a firm retrospective diagnosis of depression, who had been receiving antidepressant drugs, and 11 matched controls. Significantly lower numbers of beta-adrenoceptor binding sites were found in thalamus and temporal cortex (Brodmann area 38), but not in other brain regions, of antidepressant-treated suicides compared to controls. The lower number of beta-adrenoceptor binding sites in thalamus appeared to be related to drug treatment, whereas lower numbers of beta-adrenoceptors in temporal cortex were also found in antidepressant-free suicides.<p /> <p>Language: en</p>",
language="en",
issn="0033-3158",
doi="",
url="http://dx.doi.org/"
}