@article{ref1,
title="Blunted prolactin responses to d-fenfluramine in sociopathy. Evidence for subsensitivity of central serotonergic function",
journal="British journal of psychiatry",
year="1992",
author="O'Keane, V. and Moloney, E. and O'Neill, H. and O'Connor, A. and Smith, Clarissa and Dinan, T. G.",
volume="160",
number="",
pages="643-646",
abstract="Using a neuroendocrine probe we studied nine male offenders in a forensic hospital, convicted of murder, with a diagnosis of antisocial personality disorder, who had been behaviourally 'quiescent' for varying periods and who had not recently been abusing drugs. Nine healthy age-matched men also participated. All subjects received 30 mg d-fenfluramine (d-FEN), a 5-HT releasing agent, orally, after an overnight fast, and serial samples for prolactin estimation were taken hourly for five hours. Responses were significantly impaired in the patients, suggesting a subsensitivity of certain 5-HT systems in antisocial personality disorder, regardless of recent or ongoing behavioural disturbance.<p /> <p>Language: en</p>",
language="en",
issn="0007-1250",
doi="",
url="http://dx.doi.org/"
}