@article{ref1,
title="Cardiovascular manifestations of moderate to severe carbon monoxide poisoning",
journal="Journal of the American College of Cardiology",
year="2005",
author="Satran, Daniel and Henry, Christopher R. and Adkinson, C. and Nicholson, Caren I. and Bracha, Yiscah and Henry, Timothy D.",
volume="45",
number="9",
pages="1513-1516",
abstract="OBJECTIVES: We describe the cardiovascular manifestations of carbon monoxide (CO) poisoning. BACKGROUND: Carbon monoxide poisoning is a common cause of toxicologic morbidity and mortality. Although the neurologic sequelae of CO poisoning have been well described, the cardiovascular consequences are limited to isolated case reports. METHODS: We reviewed the cardiovascular manifestations of 230 consecutive patients treated for moderate to severe CO poisoning in the hyperbaric oxygen chamber at Hennepin County Medical Center (HCMC), a regional center for treatment of CO poisoning. RESULTS: The mean age was 47.2 years with 72% men. Ischemic electrocardiogram (ECG) changes were present in 30% of patients, whereas only 16% had a normal ECG. Cardiac biomarkers (creatine kinase-MB fraction or troponin I) were elevated in 35% of patients. In-hospital mortality was 5%. CONCLUSIONS: Cardiovascular sequelae of CO poisoning are frequent, with myocardial injury assessed by biomarkers or ECG in 37% of patients. Patients admitted to the hospital with CO poisoning should have a baseline ECG and serial cardiac biomarkers.",
language="",
issn="0735-1097",
doi="10.1016/j.jacc.2005.01.044",
url="http://dx.doi.org/10.1016/j.jacc.2005.01.044"
}