@article{ref1,
title="Relationships among premorbid alcohol use, acute intoxication, and early functional status after traumatic brain injury",
journal="Archives of physical medicine and rehabilitation",
year="2008",
author="Vickery, Chad D. and Sherer, Mark and Nick, T. G. and Nakase-Richardson, Risa and Corrigan, John D. and Hammond, Flora and Macciocchi, Stephen and Ripley, David L. and Sander, Angelle",
volume="89",
number="1",
pages="48-55",
abstract="OBJECTIVE: To investigate the relationships among intoxication at time of injury, preinjury history of problem drinking, and early functional status in patients with traumatic brain injury (TBI). DESIGN: Prospective cohort study. SETTING: Acute inpatient TBI rehabilitation. PARTICIPANTS: Participants were 1748 persons with TBI. INTERVENTIONS: Not applicable. MAIN OUTCOME MEASURES: Blood alcohol levels (BALs) were obtained at admission to the emergency department, and a history of problem drinking was obtained through interview. Study outcomes, Disability Rating Scale (DRS), and FIM instrument scores were gathered at admission to inpatient rehabilitation. RESULTS: Multivariate regression analysis revealed that BAL and a history of binge drinking were predictive of DRS, but not FIM, scores. A higher BAL was associated with poorer functional status on the DRS. Paradoxically, a history of binge drinking was associated with more intact functional status on the DRS. CONCLUSIONS: The relationships among intoxication at time of injury, history of problem drinking, and early outcome after TBI were modest. Injury severity had a more significant association with TBI functional status.<p /> <p>Language: en</p>",
language="en",
issn="0003-9993",
doi="10.1016/j.apmr.2007.07.047",
url="http://dx.doi.org/10.1016/j.apmr.2007.07.047"
}