@article{ref1,
title="Clinical significance of unsuspected rise in cardiac troponin in the setting of falls in older people",
journal="Emergency medicine journal",
year="2010",
author="Maréchaux, Sylvestre and Lubret, Remy and Delsart, Pascal and Hattabi, Medhi and Six-Carpentier, Marie-Michele and Carpentier, Emilie and Coutant, Veronique and Pinçon, Claire and Le Tourneau, Thierry and Puisieux, Francois and Goldstein, Patrick and Asseman, Philippe and Ennezat, Pierre Vladimir",
volume="27",
number="6",
pages="446-450",
abstract="OBJECTIVES: To assess the clinical significance of unsuspected rise in cardiac troponin I (cTnI) levels in elderly patients who have fallen. DESIGN: Monocentre prospective observational pilot study. PARTICIPANTS: Consecutive elderly patients (age >65 years) referred to the emergency department after being immobilised on the ground after a fall. MEASUREMENTS: Clinical, laboratory and Doppler echocardiography data were collected on admission to assess the cardiac correlates of increased cTnI. The survival endpoint was a composite of death or cardiovascular event. RESULTS: 60 patients were included in this study. Mean age was 81+/-8 years. Cardiac TnI was > or =0.05 ng/ml in at least one blood sample in 40 patients (67%). New diagnosis of cardiac disease was performed in 14 patients, 13 of them had cTnI > or =0.05 ng/ml. Transient apical ballooning was diagnosed in six patients. During a median follow-up of 92 (49-131) days death occurred in six patients, myocardial infarction in three, stroke in one and acute heart failure in five. Cardiac TnI > or =0.05 ng/ml was a predictor of these events (p=0.034). CONCLUSION: An unsuspected rise in cTnI correlates with new diagnosis of cardiac disease and is a potential marker of stress induced cardiomyopathy in elderly patients who fall. Cardiac TnI might be a strong predictor of outcome in these patients.<p /> <p>Language: en</p>",
language="en",
issn="1472-0205",
doi="10.1136/emj.2009.076406",
url="http://dx.doi.org/10.1136/emj.2009.076406"
}