@article{ref1,
title="Serotonergic function in aggressive and nonaggressive boys with attention deficit hyperactivity disorder",
journal="American journal of psychiatry",
year="1994",
author="Halperin, J. M. and Sharma, V. and Siever, Larry J. and Schwartz, S. T. and Matier, K. and Wornell, G. and Newcorn, J. H.",
volume="151",
number="2",
pages="243-248",
abstract="OBJECTIVE: This study was designed to assess central serotonergic (5-HT) function in aggressive and nonaggressive boys with attention deficit hyperactivity disorder. METHOD: Prolactin response to a challenge dose of the 5-HT agonist d,l-fenfluramine was assessed in 25 7-11-year-old boys with attention deficit hyperactivity disorder who were divided into aggressive and nonaggressive subgroups. In addition, the subgroups were compared on plasma catecholamine metabolites and platelet 5-HT. RESULTS: The aggressive group had a significantly greater prolactin response to the fenfluramine challenge than the nonaggressive subgroup. The groups did not differ on peripheral measures of neurotransmitter function. CONCLUSIONS: These data suggest that aggressive and nonaggressive children with attention deficit hyperactivity disorder differ in central 5-HT functioning.<p /><p>Language: en</p>",
language="en",
issn="0002-953X",
doi="",
url="http://dx.doi.org/"
}