@article{ref1,
title="Serum sickness reaction following multiple insect stings",
journal="Annals of allergy, asthma and immunology",
year="1995",
author="Lazoglu, A. H. and Boglioli, L. R. and Taff, M. L. and Rosenbluth, M. and Macris, N. T.",
volume="75",
number="6 Pt 1",
pages="522-524",
abstract="BACKGROUND: Anaphylaxis is the most common systemic allergic reaction caused by stinging insects. Serum sickness reactions occur much less frequently. OBJECTIVE: To determine the level of venom-specific IgG and IgE antibodies during and after a serum sickness reaction to vespid venom. METHODS: Case report; ELISA determination of venom-specific IgG and IgE; complement levels and tests for immune complexes were performed. RESULTS: We report the case of a 66-year-old woman who developed a serum sickness reaction nine days after receiving multiple vespid stings. She developed urticaria, angioedema, fever, and arthralgias. She had elevated IgG and IgE venom-specific titers which declined during the recovery phase. Complement levels were normal and tests for immune complexes were negative. She was successfully treated with venom-specific immunotherapy without any serum sickness reaction. CONCLUSIONS: A serum sickness reaction with elevated venom-specific IgG and IgE is reported with successful immunotherapy.<p /><p>Language: en</p>",
language="en",
issn="1081-1206",
doi="",
url="http://dx.doi.org/"
}