@article{ref1,
title="Recovery from a psychotropic drug overdose tends to depend on the time from ingestion to arrival, the Glasgow Coma Scale, and a sign of circulatory insufficiency on arrival",
journal="American journal of emergency medicine",
year="2007",
author="Yanagawa, Youichi and Sakamoto, Tetsuya and Okada, Y.",
volume="25",
number="7",
pages="757-761",
abstract="PURPOSE: The aim of this study was to investigate which factors on arrival correlate with the duration of unconsciousness induced by a psychotropic drug overdose. BASIC PROCEDURE: Patients were 175 consecutive intubated patients unconscious due to psychotropic drug overdose. They were divided into 2 groups, an &quot;early&quot; group in which the patients were extubated within 2 days from hospitalization, and a &quot;delayed&quot; group who were not extubated within 2 days. MAIN FINDINGS: Glasgow Coma Scale (P = .001) scores in the early group were higher than those in the delayed group. The estimated time from ingestion to admission (P < .0001), creatine kinase level (P < .01), number of cases demonstrating shock (P < .05), shock index (P < .0001), and heart rate (P = .001) in the early group were smaller than those in the delayed group. Two subjects in the delayed group died of pneumonia and pulmonary embolism. PRINCIPAL CONCLUSIONS: Delayed arrival from ingestion, a low level of unconsciousness, and a sign of circulatory insufficiency in a patient with a psychotropic drug overdose were risk factors of a delayed recovery and death.<p /><p>Language: en</p>",
language="en",
issn="0735-6757",
doi="10.1016/j.ajem.2006.12.006",
url="http://dx.doi.org/10.1016/j.ajem.2006.12.006"
}