@article{ref1,
title="Miniature hygrometric hot flash recorder",
journal="Fertility and sterility",
year="2007",
author="Freedman, Robert R. and Wasson, Samuel",
volume="88",
number="2",
pages="494-496",
abstract="OBJECTIVE: To design and test a miniature ambulatory hot flash recorder that uses neither electrodes nor gel. DESIGN: In the first study, putative hot flashes recorded by using a relative humidity sensor were compared with patient event marks. In the second study, relative humidity recorded by using a complete prototype recorder was compared with sternal skin conductance recordings made on a Biolog recorder, as well as with event marks. SETTING: University medical center. PATIENT(S): Ten healthy postmenopausal women reporting frequent hot flashes and using no medication. INTERVENTION(S): Body heating in laboratory. MAIN OUTCOME MEASURE(S): Positive predictive value (PPV), sensitivity, specificity. RESULT(S): In both laboratory studies, the PPV, sensitivity, and specificity among all three measures (relative humidity, skin conductance level, event) were 100%. In the field, a relative humidity increase of 3% per minute compared with skin conductance level-detected hot flashes yielded a PPV of 95.6%, a specificity of 95.2%, and a sensitivity of 90.9%. CONCLUSION(S): This device should be useful as an endpoint in clinical trials of treatments for hot flashes.<p /><p>Language: en</p>",
language="en",
issn="0015-0282",
doi="10.1016/j.fertnstert.2006.11.184",
url="http://dx.doi.org/10.1016/j.fertnstert.2006.11.184"
}