@article{ref1,
title="Effect of off-road competitive motocross race on plasma oxidative stress and damage markers",
journal="British journal of sports medicine",
year="2007",
author="Ascensão, António and Ferreira, Rita and Marques, Franklim and Oliveira, Eduardo and Azevedo, Victor and Soares, José and Magalhães, José",
volume="41",
number="2",
pages="101-105",
abstract="AIM: To analyse the effect of an off-road motocross heat on plasma levels of oxidative stress and damage, blood leucocyte counts and urine catecholamine concentration. METHODS: Plasma contents of total, reduced and oxidised (GSSG) glutathione, %GSSG, malondialdehyde (MDA), protein carbonyl and sulphydryl groups, total antioxidant status (TAS), uric acid, and blood neutrophil and lymphocyte counts were evaluated in 10 male top-level riders before, immediately after (0 h) and 1 h after a simulated competitive motocross race. 24-h urine adrenaline, noradrenaline and dopamine concentrations were also measured. RESULTS: The motocross heat resulted in an increase in plasma oxidative stress and damage (p<0.05). This was shown by a significant increase in %GSSG, TAS, MDA and carbonyls, and by a decrease in sulphydryl groups after the race. There was a significant increase in both plasma uric acid and urine catecholamine concentration after the race (p<0.05). Blood neutrophil counts increased at 0 and 1 h after exercise (p<0.05). Lymphocyte count increased from baseline to 0 h, although it decreased from baseline and 0 to 1 h after exercise (p<0.05). CONCLUSION: The data reinforce the marked metabolic and hormonal demands imposed by motocross, resulting in a condition of enhanced plasma oxidative stress and damage.<p /><p>Language: en</p>",
language="en",
issn="0306-3674",
doi="10.1136/bjsm.2006.031591",
url="http://dx.doi.org/10.1136/bjsm.2006.031591"
}