@article{ref1,
title="Severe affective and behavioural dysregulation is associated with significant psychosocial adversity and impairment",
journal="Journal of child psychology and psychiatry",
year="2011",
author="Jucksch, Viola and Salbach-Andrae, Harriet and Lenz, Klaus and Goth, Kirstin and Döpfner, Manfred and Poustka, Fritz and Freitag, Christine M. and Lehmkuhl, Gerd and Lehmkuhl, Ulrike and Holtmann, Martin",
volume="52",
number="6",
pages="686-695",
abstract="Background:  Recently, a highly heritable behavioral phenotype of simultaneous deviance on the Anxious/Depressed, Attention Problems, and Aggressive Behavior syndrome scales has been identified on the Child Behavior Checklist (CBCL-Dysregulation Profile, CBCL-DP). This study aims to investigate psychosocial adversity and impairment of the CBCL-DP. Methods:  A total of 9024 patients aged 4-18 years were assessed using the CBCL, and the axes V and VI of ICD-10. Results:  ANOVA revealed significant differences regarding psychosocial adversity and impairment between patients with CBCL-DP phenotype and the clinical control group, patients with attention problems, and patients with attention problems and additional anxious/depressed symptoms as assessed by the CBCL. Patients with CBCL-DP showed significant psychosocial adversity and impairment. However, in most cases patients with aggressive behavior showed equal psychosocial adversity as patients with CBCL-DP. Conclusions:  Findings suggest the CBCL-DP phenotype to be associated with significant psychosocial adversity and impairment either as a cause or an effect of the syndrome. Clinicians should carefully address psychosocial adversity and impairment with particular attention to the adversity and impairment of adolescents with CBCL-DP.<p /> <p>Language: en</p>",
language="en",
issn="0021-9630",
doi="10.1111/j.1469-7610.2010.02322.x",
url="http://dx.doi.org/10.1111/j.1469-7610.2010.02322.x"
}