@article{ref1,
title="Nonsteroidal anti-inflammatory drugs and coma: a case report of fenoprofen overdose",
journal="Annals of emergency medicine",
year="1990",
author="Kolodzik, J. M. and Eilers, M. A. and Angelos, M. G.",
volume="19",
number="4",
pages="378-381",
abstract="We present the case of a 17-year-old girl who ingested 24 to 36 g fenoprofen as a suicidal gesture. She presented with coma, hypotension, metabolic acidosis, and respiratory depression within four hours of ingestion. The most common adverse effects of the nonsteroidal anti-inflammatory drugs occur in both therapeutic and toxic doses and include gastrointestinal upset, blood dyscrasias, and analgesic nephropathy. The propionic acid derivatives of nonsteroidal anti-inflammatory drugs, including fenoprofen and ibuprofen, are rarely associated with severe toxic effects. This is the first report of pure fenoprofen overdose presenting as coma and metabolic acidosis.<p /><p>Language: en</p>",
language="en",
issn="0196-0644",
doi="",
url="http://dx.doi.org/"
}