@article{ref1,
title="The expression of schizophrenia, affective disorder and vulnerability to tardive dyskinesia in an extensive pedigree",
journal="British journal of psychiatry",
year="1988",
author="Waddington, J. L. and Youssef, H. A.",
volume="153",
number="",
pages="376-381",
abstract="The demography, psychiatric morbidity, and motor consequences of long-term neuroleptic treatment in the 14 children born to a father with a family history of chronic psychiatric illness and a mother with a late-onset affective disorder resulting in suicide are documented. Twelve siblings lived to adulthood, nine of whom were admitted to a psychiatric hospital in their second or third decade, and required continuous in-patient care; five remaining in hospital, with long-term exposure to neuroleptics, had chronic, deteriorating, schizophrenic illness and emergence of movement disorder. Two siblings showed no evidence of psychosis but developed a late-onset affective disorder. The implications for the issues of homotypia, vulnerability to involuntary movements, and interaction with affective disorder are discussed.<p /><p>Language: en</p>",
language="en",
issn="0007-1250",
doi="",
url="http://dx.doi.org/"
}