
@article{ref1,
title="Topiramate overdose: a case report of a patient with extremely high topiramate serum concentrations and nonconvulsive status epilepticus",
journal="Epilepsia",
year="2010",
author="Brandt, Christian and Elsner, Heike and Füratsch, Nora and Hoppe, Matthias and Nieder, Esther and Rambeck, Bernhard and Ebner, Alois and May, Theodor W.",
volume="51",
number="6",
pages="1090-1093",
abstract="We report the case of a 21-year-old man with idiopathic generalized epilepsy who ingested about 8,000 mg of topiramate (TPM) in a suicide attempt. On admission to the hospital he had a nonconvulsive status epilepticus and received 4 mg lorazepam i.v. He recovered rapidly despite an initial TPM concentration of 144.6 microg/ml. To our knowledge, this is the first report of a patient who survived such a high TPM concentration. The case indicates that nonconvulsive status epilepticus could be a manifestation of TPM intoxication.<p /> <p>Language: en</p>",
language="en",
issn="0013-9580",
doi="10.1111/j.1528-1167.2009.02395.x",
url="http://dx.doi.org/10.1111/j.1528-1167.2009.02395.x"
}