@article{ref1,
title="Unaltered alpha(2)-noradrenergic/imidazoline receptors in suicide victims: a postmortem brain autoradiographic analysis",
journal="European Neuropsychopharmacology",
year="2000",
author="Gross-Isseroff, R. and Weizman, A. and Fieldust, S. J. and Israeli, M. and Biegon, A.",
volume="10",
number="4",
pages="265-271",
abstract="In vitro quantitative autoradiography of alpha(2)-adrenergic/imidazoline receptors, using [(125)I]iodoclonidine as a ligand, was performed on 24 human brains postmortem. Twelve brains were obtained from suicide victims and 12 from matched controls. We found no significant, region-dependent alterations in the density of alpha(2)-adrenergic receptors in brains of suicide victims as compared to matched controls. We also report age-dependent reductions in binding in the prefrontal cortex and hippocampus, as well as significant recent alcohol ingestion-dependent reductions in binding in the prefrontal cortex. Sex and time from death to autopsy did not affect iodoclonidine binding in our sample.<p /><p>Language: en</p>",
language="en",
issn="0924-977X",
doi="",
url="http://dx.doi.org/"
}