
@article{ref1,
title="Fatal overdose of clozapine",
journal="Forensic science international",
year="1997",
author="Keller, T. and Miki, A. and Binda, S. and Dirnhofer, R.",
volume="86",
number="1-2",
pages="119-125",
abstract="An ingestion of an unknown quantity of Leponex (clozapine) tablets in a suicide is described. Although clozapine is known for over 30 years now, relatively few cases of intoxications due to clozapine overdose have been reported. The authors report a new and quick method to analyze and determine the clozapine and N-desmethylclozapine concentration in body fluids. The analytes and an internal standard (zolpidem) were extracted from alkalinized samples into ethyl acetate before GC/NPD analysis. The proposed method resulted in a rapid procedure most useful in cases of deliberate poisoning with the neuroleptic drug Leponex.<p /><p>Language: en</p>",
language="en",
issn="0379-0738",
doi="",
url="http://dx.doi.org/"
}