@article{ref1,
title="Hemolysis after acetaminophen overdose in a patient with glucose-6-phosphate dehydrogenase deficiency",
journal="Journal of toxicology - clinical toxicology",
year="1996",
author="Wright, R. O. and Perry, H. E. and Woolf, A. D. and Shannon, M. W.",
volume="34",
number="6",
pages="731-734",
abstract="CASE REPORT: A sixteen year-old-male with a history of glucose-6-phosphate dehydrogenase deficiency ingested an unknown amount of acetaminophen and presented to an emergency department 7.5 h later. He was afebrile. His serum acetaminophen level was 184 micrograms/mL, and his urine toxicologic screen was otherwise negative. Vomiting led to enrollment in a experimental protocol of intravenous N-acetylcysteine. He developed no evidence of subsequent chemical hepatitis but did develop a significant Coomb's negative hemolytic anemia. Hemoglobin on presentation was 14 g/dL and reached a nadir of 9.4 g/dL on admission day 4. CONCLUSION: Patients with glucose-6-phosphate dehydrogenase deficiency who overdose with acetaminophen should be monitored for the possible development of subsequent drug-induced hemolysis.<p /><p>Language: en</p>",
language="en",
issn="0731-3810",
doi="",
url="http://dx.doi.org/"
}