@article{ref1,
title="Azathioprine ingestion with suicidal intent by an adolescent with chronic juvenile polyarthritis",
journal="Klinische padiatrie",
year="1998",
author="Krüger, C. and Jüngert, J. and Schmitt-Grohe, S. and Beese, M. and Ruder, H.",
volume="210",
number="3",
pages="136-138",
abstract="We report on a 13 years 7 months old boy who ingested 650 mg azathioprine in a suicide attempt. His baseline medication was azathioprine and methotrexate for control of juvenile chronic polyarthritis. After the induction of vomiting by ipecacuanha sirup and administration of charcoal (1 g/kg), he was closely followed for haematological, hepatic, and renal side effects. During the following days, no serious adverse events were noted except that the thrombocyte (from 403,000 down to 199,000/microliter) and total leukocyte count decreased moderately (from 12,000 down to 7100/microliter). On the basis of this case report and the available literature, the potential acute toxicity of azathioprine and possible treatment modalities are discussed.<p /><p>Language: de</p>",
language="de",
issn="0300-8630",
doi="10.1055/s-2008-1043866",
url="http://dx.doi.org/10.1055/s-2008-1043866"
}