
@article{ref1,
title="Decreased platelet [3H]paroxetine binding sites in suicide attempters",
journal="Psychiatry research",
year="2001",
author="Marazziti, D. and Dell'Osso, L. and Rossi, A. and Masala, I. and Baroni, S. and Armani, A. and Giannaccini, G. and Di Nasso, E. and Lucacchini, A. and Cassano, G. B.",
volume="103",
number="2-3",
pages="125-131",
abstract="Research to date would suggest the possible involvement of the serotonin (5-HT) system in the pathophysiology of suicide. With this study, we aimed to investigate the platelet 5-HT transporter, by means of the specific binding of tritiated paroxetine ([3H]Par), in a sample of 20 suicide attempters recruited at a first-aid service, as compared with healthy control subjects and psychiatric patients with no current or previous history of suicide attempt. The results, showing a decreased number of [3H]Par binding sites in suicide attempters, would suggest the involvement of the presynaptic 5-HT transporter in self-aggressive behavior.<p /><p>Language: en</p>",
language="en",
issn="0165-1781",
doi="",
url="http://dx.doi.org/"
}